It seems to us that you have your javascript turned off on your browser. Javascript is required in order for our site to behave correctly. Please enable your javascript to continue use our site. Smarter decisions, better care uptodate synthesizes the most recent medical information into evidence-based practical recommendations clinicians trust to make the right point of care decisions. Rigorous editorial process: evidence-based treatment recommendations world-renowned physician authors: over 5,100 physician authors around the globe innovative technology: integrates into the workflow; access from emrs for more information, click below. Clinicians institutions group practices patients subscribers log in here related articles head and neck squamous cell carcinoma of unknown primary initial systemic therapy for advanced non-small cell lung cancer without an epidermal growth factor receptor mutation or the alk fusion oncogene overview of the classification and management of neoplasms of unknown primary site overview of the initial evaluation, treatment and prognosis of lung cancer poorly differentiated carcinoma of unknown primary site related searches squamous cell carcinoma of unknown primary site carcinoma of unknown primary metastatic cancer cervical lymphadenopathy inguinal lymphadenopathy malignancy metastatic non-small cell lung cancer squamous cell carcinoma squamous cell carcinoma of unknown primary site authors john d hainsworth, md f anthony greco, md section editor george p canellos, md deputy editor michael e ross, md topic outline introduction upper or mid cervical lymph nodes lower cervical or supraclavicular nodes inguinal lymph node disease other metastatic sites summary and recommendations references introduction cancer of unknown primary site (cup) is a relatively common clinical entity, accounting for 4 to 5 percent of all invasive cancers [1]. Within this category, tumors from many primary sites with varying biology are represented. Squamous cell carcinomas (sccs) comprise approximately 5 percent of cups. (see "overview of the classification and management of neoplasms of unknown primary site". ) effective treatment is available for some patients with scc of unknown primary site who fit certain clinical syndromes, particularly those with involvement of the cervical or inguinal lymph nodes. cheap viagra online viagra for sale viagra for sale buy generic viagra buy generic viagra viagra without a doctor prescription cheap generic viagra cheap viagra cheap generic viagra For this reason, appropriate evaluation of these patients is essential prior to embarking on treatment. Cervical lymph nodes are the most common metastatic site for sccs. Patients with tumor involving upper or mid level cervical nodes are likely to have a primary cancer of the head and n.